Apigenin: The Anxiolytic Constituent ofTurnera aphrodisiaca.

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Apigenin: The Anxiolytic Constituent of Turnera aphrodisiaca

Turnera aphrodisiacaWard (Turneraceae) has been traditionally used for the treatment of anxiety neurosis and as aphrodisiac, but no attempts have been made to investigate the plant systematically for its traditional claims. The current investigation was carried out ot isolate the bioactive constituent(s) from T. aphrodisiaca using bioactivity-guided fractionation. Antianxiety activityguided fra...

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Estimation of Apigenin, an Anxiolytic Constituent, in Turnera aphrodisiaca

An HPTLC densitometric method has been developed to estimate apigenin in Turnera aphrodisiaca aerial and its segregated parts (leaves, stems, flowers and fruits) so that plant can be standardized on the basis of its bioactive marker. The apigenin content in methanol extract of T. aphrodisiaca aerial parts was found to be about fourteen times less than acid hydrolyzed methanol extract of the pla...

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Anti-anxiety Activity Studies on Homoeopathic Formulations of Turnera aphrodisiaca Ward

Turnera aphrodisiaca Ward (Turneraceae) has been traditionally used for the treatment of anxiety neurosis, and as an aphrodisiac. Mother tinctures (85% ethanol extracts) of T. aphrodisiaca have also been used for the treatment of central nervous system disorders. In the present investigation, T. aphrodisiaca mother tinctures formulated by three reputed manufacturers of homoeopathic medicines (N...

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Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.

OBJECTIVES To review and describe studies of the non-psychotomimetic constituent of Cannabis sativa, cannabidiol (CBD), as an anxiolytic drug and discuss its possible mechanisms of action. METHOD The articles selected for the review were identified through searches in English, Portuguese, and Spanish in the electronic databases ISI Web of Knowledge, SciELO, PubMed, and PsycINFO, combining the...

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Extracts of the pepper plant kava (Piper methysticum) are effective in alleviating anxiety in clinical trials. Despite the long-standing therapeutic interest in kava, the molecular target(s) of the pharmacologically active constituents, kavalactones have not been established. γ-Aminobutyric acid type A receptors (GABAARs) are assumed to be the in vivo molecular target of kavalactones based on d...

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ژورنال

عنوان ژورنال: Pharmaceutical Biology

سال: 2006

ISSN: 1388-0209,1744-5116

DOI: 10.1080/13880200600591758